Parkinson’s disease (Vorum Tremens)
Parkinson (Vorum tremens) is a chronic progressive disease of the brain was first described in 1817 by J. Parkinson. Patients with Parkinson’s disease often experience involuntary trembling limbs (tremor), muscle rigidity, impaired coordination and speech, and difficulty moving. These symptoms usually occurs after age 60, but cases of Parkinson’s disease at the age of 50 years are known.
disease Parkinson’s is a progressive disease, meaning that its symptoms and the final appearance exacerbated. However, despite the fact that ultimately leads to Parkinson’s disease with a physical disability and loss of ability to slow disease progression, and also according to the diagnosis of most patients at the earliest for many years may lead to quality life.
Unlike other serious neurological disorders, Parkinson’s disease are being treated. Often, drugs, or an implant in a station of the brain of special equipment to stimulate brain activity. In extreme cases, surgery – brain surgery, a method, the essence stereo taxis consists of the destruction of a small area of subcrustal structures of the brain. Seek more effective treatments for Parkinson’s disease are being pursued.
The symptoms of Parkinson’s disease
disease The first symptoms of Parkinson’s disease is difficult to notice, as inertia of the hand off, a slight tremor in the fingers of one hand or insignificant violations of speech. Patients feel a devastation, a breakdown, depression or with severe insomnia. In addition to the normal use (shower, shave, kitchen, etc.) require considerable efforts and hire more time. symptoms
* tremors. The earthquake often starts with a little trembling hands or fingers, or individual. Sometimes the hand tremor is irregular movements of large and medium finger turning points along the invisible (what is called “the conduct of a syndrome of pills”). Sometimes there is a tremor of lower limbs. These symptoms may be expressed on one side of the body or taken as symmetrical and other symptoms of the defeat of the nervous system are combined. The earthquake was particularly due to violations of coordination, sensitivity, if the patient has shown in a state of stress. Even though the shaking of the members caused significant inconvenience, it does not lead to the loss of capacity, and disappears only when the patient is asleep. Many patients with Parkinson’s disease suffer only a slight tremor.
* slow movements (tremor). In Parkinson’s disease “acquire” new symptoms, including slowness and clumsiness of movements, and the violation of coordination. Stiffness of muscles of the legs can complicate the speed is broken. It is characterized particularly concerned about the complexity of the performance of basic actions.
* muscle rigidity. Often there is a stiff neck muscles and limbs. In some cases, even by vertical movements of stiffness and pain.
* loss of balance. Parkinson’s disease, especially in a serious condition, it is often the inability to maintain balance with. For many years, this problem is insignificant and is not unpleasant.
* the loss of automatic movements. Flashes appearance of a smile and hands to grow up – automatic share of a normal organism, which is conducted at a subconscious level, and also next to our request. In patients with Parkinson’s disease such automatic movements often disappear, and sometimes disappears completely. In some cases, fixed on the individual patient’s expression of intense and sustained attention, eye gaze. In some patients, with the exception of a facial expression, gestures, the ability to disappear.
* against a violation of the joint. Many patients also suffer from the violation of the word – it can be easily modulated, illegible. The lost voice intonations and monotonous and is silent. For seniors, it is particularly problematic, more co-hear how people can not easily hear.
* violation of swallowing and increased salivation. This symptom appears in late stages of disease development, but, with rare exceptions, patients with the condition are still able to accept what in the diet.
* dementia. The negligible percentage of patients with dementia – an inability to think, understand and remember. This symptom seems to be in the final phase of the disease. Although dementia is an indicator of Alzheimer’s disease examined more often, and it can accompany other serious diseases, including Parkinson’s disease. In this case, the delay of the thought processes and inability to concentrate certify the onset of dementia. />
For the 200 years since the moment the opening of Parkinson’s disease was possible, scientists, certain aspects of these processes to understand for complex diseases.
Today is known to develop many symptoms of Parkinson’s disease and performances, damage or destruction of certain nerve endings, is substantia nigra of the brain. In a normal state of these dopaminergic neurons develop. Function of dopamine is the smooth transmission of impulses to the maintenance of normal movement. In Parkinson’s disease, reducing the production of dopamine, the normal transmission of nerve impulses is disrupted and there are some basic symptoms of Parkinson’s disease.
While all older people lose part of the evolution of neutron dopamine. But in patients with Parkinson’s disease lose more than half of the neutrons in the substantia nigra is. Although there is a degeneration of brain cells and others, the development of dopaminergic cells are required for movement, so that the loss is catastrophic. The reasons for the deterioration or destruction of these cells is still the subject of numerous investigations. Scientists believe that Parkinson’s disease to develop because of an unfavorable combination of genetic and environmental factors. Some drugs, diseases and poisons can also typical clinical features of Parkinson’s disease.
